Methylophiopogonanone A(R-Methylophiopogonanone A)
Methylophiopogonanone A
CAS: 74805-92-8
Molecular Formula: C19H18O6
Methylophiopogonanone A(R-Methylophiopogonanone A) - Names and Identifiers
Methylophiopogonanone A(R-Methylophiopogonanone A) - Physico-chemical Properties
| Molecular Formula | C19H18O6 |
| Molar Mass | 342.34 |
| Density | 1.410 |
| Melting Point | 166-167°C |
| Boling Point | 580.1±50.0 °C(Predicted) |
| Specific Rotation(α) | (c, 1 in CHCl3)-72 |
| Solubility | Easily soluble in chloroform, acetone, slightly soluble in methanol. |
| Appearance | Colorless needle crystal |
| pKa | 8.24±0.40(Predicted) |
| Storage Condition | 2-8℃ |
| Physical and Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents, derived from Ophiopogon japonicus fibrous root Ophiopogon japonicus.. |
| In vitro study | Methylophiopogonanone A (MO-A; 10 μmol/L) significantly decreases apoptosis and cleaved caspase-3 expression, elevated the Bcl-2/Bax ratio and restored NO production. Pretreatment with Methylophiopogonanone A (MO-A) markedly increases the activation of PI3K/Akt/eNOS pathway in H9C2 cells subjected to H/R, and the protective effects of MO-A are abolished in the presence of the PI3K inhibitor wortmannin (100 nmol/L). |
| In vivo study | Methylophiopogonanone A (MO-A;10 mg/kg/d, po) for 2 weeks) protects cardiac function following myocardial I/R injury. |
Methylophiopogonanone A(R-Methylophiopogonanone A) - Reference
| Reference Show more | 1. [IF=6.529] Lingna Wu et al."Interactions of the major effective components in Shengmai formula with breast cancer resistance protein at the cellular and vesicular levels."Biomed Pharmacother. 2021 Jan;133:110939 2. [IF=5.34] Tao Zhan et al."The major effective components in Shengmai Formula interact with sodium taurocholate co-transporting polypeptide."Phytomedicine. 2019 Jun;59:152916 3. [IF=4.36] Yang Zhao et al."Shashen-Maidong Decoction improved chronic intermittent hypoxia-induced cognitive impairment through regulating glutamatergic signaling pathway."J Ethnopharmacol. 2021 Jun;274:114040 |
Methylophiopogonanone A(R-Methylophiopogonanone A) - Introduction
Methylophiopogonanone A (Makicetone A) is A natural alkaloid, belonging to the class of glutinin compounds. The following is a description of its nature, use, preparation and safety information:
Nature:
Methylophiopogonanone A is A colorless or light yellow solid. It has a certain solubility, soluble in organic solvents such as alcohols and ethers. Common forms are crystalline or powder.
Use:
Methylophiopogonanone A has important applications in the field of medicine and cosmetics. It has been found to have certain antioxidant, anti-inflammatory, anti-tumor, anti-allergic, anti-viral and other activities, so it can be used to prepare drugs or health products. In addition, it is also used in skin care products as skin care agents, moisturizers and anti-aging agents.
Preparation Method:
The preparation method of methyllophiopogonanone A is mainly based on natural sources. One commonly used method of preparation is extraction and isolation from Ophiopogon japonicus. Generally, high purity methyllophiopogonanone A can be obtained by alcohol extraction, solvent separation, crystallization purification and other steps.
Safety Information:
The current study shows that methyllophiopogonanone A is safe in humans at recommend doses. However, for excessive intake or sensitive people, adverse reactions may occur. Therefore, when using or contacting methyllophiopogonanone A, you should carefully read and follow the relevant instructions for use, avoid excessive use or avoid contact with sensitive people. In case of discomfort or unclear conditions, it is recommended to consult a professional doctor or chemist.
Nature:
Methylophiopogonanone A is A colorless or light yellow solid. It has a certain solubility, soluble in organic solvents such as alcohols and ethers. Common forms are crystalline or powder.
Use:
Methylophiopogonanone A has important applications in the field of medicine and cosmetics. It has been found to have certain antioxidant, anti-inflammatory, anti-tumor, anti-allergic, anti-viral and other activities, so it can be used to prepare drugs or health products. In addition, it is also used in skin care products as skin care agents, moisturizers and anti-aging agents.
Preparation Method:
The preparation method of methyllophiopogonanone A is mainly based on natural sources. One commonly used method of preparation is extraction and isolation from Ophiopogon japonicus. Generally, high purity methyllophiopogonanone A can be obtained by alcohol extraction, solvent separation, crystallization purification and other steps.
Safety Information:
The current study shows that methyllophiopogonanone A is safe in humans at recommend doses. However, for excessive intake or sensitive people, adverse reactions may occur. Therefore, when using or contacting methyllophiopogonanone A, you should carefully read and follow the relevant instructions for use, avoid excessive use or avoid contact with sensitive people. In case of discomfort or unclear conditions, it is recommended to consult a professional doctor or chemist.
Last Update：2024-04-09 20:48:19
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CAS: 74805-92-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Methylophiopogonanone A Visit Supplier Webpage Request for quotationCAS: 74805-92-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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